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Pronounced: Nor-OX-in
Generic name: Norfloxacin

Why is this drug prescribed?

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Noroxin is an antibacterial medication used to treat infections of the urinary tract, including cystitis (inflammation of the inner lining of the bladder caused by a bacterial infection), prostatitis (inflammation of the prostate gland), and certain sexually transmitted diseases, such as gonorrhea.

Most important fact about this drug

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Noroxin is not given for the treatment of syphilis. When used in high doses for a short period of time to treat gonorrhea, it may actually mask or delay the symptoms of syphilis. Your doctor may perform certain tests for syphilis at the time of diagnosing gonorrhea, and after treatment with Noroxin.

How should you take this medication?

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Noroxin should be taken, with a glass of water, either 1 hour before or 2 hours after eating a meal or drinking milk. Do not take more than the dosage prescribed by your doctor.

It is important to drink plenty of fluids while taking Noroxin.

Take all the Noroxin your doctor prescribes. If you stop taking the medicine too soon, you may have a relapse.

--If you miss a dose...

Be sure to take it as soon as possible. This will help to keep a constant amount of Noroxin in your body. However, if it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take two doses at the same time.

--Storage instructions...

Store at room temperature. Keep container tightly closed. Store out of reach of children.

What side effects may occur?

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Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine whether it is safe for you to continue taking Noroxin.


  • More common side effects may include:
    Abdominal cramping, dizziness, headache, nausea, weakness


  • Other side effects may include:
    Abdominal pain or swelling, allergies, anal itching, anal/rectal pain, anxiety, arthritis, back pain, bitter taste, blood abnormalities, blurred vision, bursitis, chest pain, chills, confusion, constipation, depression, diarrhea, difficult breathing, double vision, dry mouth, extreme sleepiness, fever, fluid retention and swelling, gas, heart attack, heartburn, heart palpitations, hives, indigestion, insomnia, intestinal inflammation, itching, joint pain, kidney failure (symptoms may include reduced amount of urine, drowsiness, nausea, vomiting, and coma), lack of coordination, loose stools, loss of appetite, menstrual disorders, mouth ulcer, muscle pain, peeling skin, rash, reddened skin, ringing in the ears, severe skin reaction to light, stomach pain, sweating, swelling of feet or hands, temporary hearing loss, tendon inflammation or tearing, tingling in fingers, vision problems, vomiting, yellow eyes and skin


Why should this drug not be prescribed?

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You should not be using Noroxin if you are sensitive to it or to other drugs of the same type, such as Cipro, or if you have suffered tendon inflammation or tearing due to the use of such drugs. See "Special Warnings" section.

Special warnings about this medication

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Noroxin is not recommended for:

Children (under the age of 18)
Nursing mothers
Pregnant women

People with disorders such as epilepsy, severe cerebral arteriosclerosis, and other conditions that might lead to seizures should use Noroxin cautiously. There have been reports of convulsions in some people taking Noroxin.

Use Noroxin with caution if you suffer from the disease Myasthenia gravis. Noroxin may cause life-threatening respiratory problems under these circumstances.

If you develop diarrhea, tell your doctor. It could be a symptom of a potentially serious intestinal inflammation.

Some people taking drugs chemically similar to Noroxin have experienced severe, sometimes fatal reactions, occasionally after only one dose. These reactions may include: Confusion, convulsions, difficulty breathing, hallucinations, heart collapse, hives, increased pressure in the head, itching, light-headedness, loss of consciousness, psychosis, rash, restlessness, shock, swelling in the face or throat, tingling, tremors.

If you experience any of these reactions you should immediately stop taking Noroxin and seek medical help.

There is a small chance that Noroxin may weaken the muscle tendons in your shoulder, hand, or heel, causing them to tear. Should this happen, surgery or at least a long period of disability would be in store. If you feel any pain, inflammation, or tearing, stop taking this drug immediately and call your doctor. Rest and avoid exercise until the doctor is certain the tendons are intact.

Some people find needle-shaped crystals in their urine after taking Noroxin. Drink plenty of fluids while taking Noroxin. This will increase urine output and reduce crystallization.

Noroxin may cause dizziness or light-headedness and might impair your ability to drive a car or operate potentially dangerous machinery. Use caution when undertaking any activities that require full alertness if you are unsure of your ability.

You should avoid excessive exposure to direct sunlight while taking Noroxin. Stop taking Noroxin and contact your doctor immediately if you have a severe reaction to sunlight, such as a skin rash.

Possible food and drug interactions when taking this medication

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If Noroxin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Noroxin with the following:

Antacids such as Maalox and Tums
Caffeine (including coffee, tea, and some soft drinks)
Calcium supplements
Cyclosporine (Sandimmune, Neoral)
Didanosine (Videx)
Multivitamins and other products containing iron or zinc
Nitrofurantoin (Macrodantin, Macrobid)
Oral blood thinners such as warfarin (Coumadin)
Probenecid (Benemid)
Sucralfate (Carafate)
Theophylline (Theo-Dur)

Special information if you are pregnant or breastfeeding

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The effects of Noroxin during pregnancy have not been adequately studied. Inform your doctor if you are pregnant or planning a pregnancy.

Do not take Noroxin while breastfeeding. There is a possibility of harm to the infant.

Recommended dosage

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Take Noroxin with a full glass of water 1 hour before, or 2 hours after, eating a meal or drinking milk. Drink plenty of liquids while taking Noroxin.

Uncomplicated Urinary Tract Infections

The suggested dose is 800 milligrams per day; 400 milligrams should be taken twice a day for 3 to 10 days, depending upon the kind of bacteria causing the infection. People with impaired kidney function may take 400 milligrams once a day for 3 to 10 days.

Complicated Urinary Tract Infections

The suggested dose is 800 milligrams per day; 400 milligrams should be taken twice a day for 10 to 21 days.


The usual daily dose is 800 milligrams, divided into 2 doses of 400 milligrams each, taken for 28 days.

Sexually Transmitted Diseases (Gonorrhea)

The usual recommended dose is one single dose of 800 milligrams for 1 day.

The total daily dosage of Noroxin should not be more than 800 milligrams.


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The symptoms of overdose with Noroxin are not known. However, any medication taken in excess can have serious consequences. If you suspect a Noroxin overdose, seek medical help immediately



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